New Research in Children: MicroRNAs in Blood Linked with Sleep Duration0

A simple blood test could provide a reliable metric to tell if children are sleeping enough, according to new research published in Experimental Physiology this week.

Researchers at the Institute of Food Sciences of the National Research Council in Italy studied children and adolescents of normal weight (based on body mass index) from eight European countries (Spain, Italy, Cyprus, Germany, Belgium, Estonia, Hungary, and Sweden) who were either “short sleepers” or “normal sleepers,” according to self-reporting.

“Short sleepers” included children sleeping less than 9 hours per day, and adolescents sleeping less than 8 hours per day. “Normal sleepers” included children sleeping at least 9 hours per day, and adolescents sleeping at least 8 hours per day.

They looked at microRNAs in their blood, which are molecules that influence which of our genes are switched on, and found that certain microRNAs had significantly different levels depending on whether the children were short or normal sleepers. The researchers took country of origin, age, sex, pubertal status, average daily screen time, and highest educational level of parents into account, showing that none of these factors was affected the microRNA levels.

These results could provide the basis for a test that could serve not only to assess sleep hygiene, but to determine susceptibility to a range of health conditions. Rather than relying on self-reporting, as we don’t often remember how much we slept farther back than a few days, this blood test could provide a more reliable metric.

Fabio Laura, one of the authors of the study, says in a release, “Our findings show for the first time that the sleep duration reflects the profile of specific circulating microRNAs in school-aged children and adolescents. This could allow clinicians to easily determine if children are sleeping enough by using a simple blood test and use this as an indication of other aspects of their health.”

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